Developing Efficient Discrete Simulations on Multicore and GPU Architectures

In this paper we show how to efficiently implement parallel discrete simulations on multicoreandGPUarchitecturesthrougharealexampleofanapplication: acellularautomatamodel of laser dynamics. We describe the techniques employed to build and optimize the implementations using OpenMP and CUDA frameworks. We have evaluated the performance on two different hardware platforms that represent different target market segments: high-end platforms for scientific computing, using an Intel Xeon Platinum 8259CL server with 48 cores, and also an NVIDIA Tesla V100GPU,bothrunningonAmazonWebServer(AWS)Cloud;and on a consumer-oriented platform, using an Intel Core i9 9900k CPU and an NVIDIA GeForce GTX 1050 TI GPU. Performance results were compared and analyzed in detail. We show that excellent performance and scalability can be obtained in both platforms, and we extract some important issues that imply a performance degradation for them. We also found that current multicore CPUs with large core numbers can bring a performance very near to that of GPUs, and even identical in some cases.Ministerio de Economía, Industria y Competitividad, Gobierno de España (MINECO), and the Agencia Estatal de Investigación (AEI) of Spain, cofinanced by FEDER funds (EU) TIN2017-89842

AER Spiking Neuron Computation on GPUs: The Frame-to-AER Generation

Neuro-inspired processing tries to imitate the nervous system and may resolve complex problems, such as visual recognition. The spike-based philosophy based on the Address-Event-Representation (AER) is a neuromorphic interchip communication protocol that allows for massive connectivity between neurons. Some of the AER-based systems can achieve very high performances in real-time applications. This philosophy is very different from standard image processing, which considers the visual information as a succession of frames. These frames need to be processed in order to extract a result. This usually requires very expensive operations and high computing resource consumption. Due to its relative youth, nowadays AER systems are short of cost-effective tools like emulators, simulators, testers, debuggers, etc. In this paper the first results of a CUDA-based tool focused on the functional processing of AER spikes is presented, with the aim of helping in the design and testing of filters and buses management of these systems.Ministerio de Educación y Ciencia TEC2009-10639-C04-0

An Approach to Distance Estimation with Stereo Vision Using Address-Event-Representation

Image processing in digital computer systems usually considers the visual information as a sequence of frames. These frames are from cameras that capture reality for a short period of time. They are renewed and transmitted at a rate of 25-30 fps (typical real-time scenario). Digital video processing has to process each frame in order to obtain a result or detect a feature. In stereo vision, existing algorithms used for distance estimation use frames from two digital cameras and process them pixel by pixel to obtain similarities and differences from both frames; after that, depending on the scene and the features extracted, an estimate of the distance of the different objects of the scene is calculated. Spike-based processing is a relatively new approach that implements the processing by manipulating spikes one by one at the time they are transmitted, like a human brain. The mammal nervous system is able to solve much more complex problems, such as visual recognition by manipulating neuron spikes. The spike-based philosophy for visual information processing based on the neuro-inspired Address-Event-Representation (AER) is achieving nowadays very high performances. In this work we propose a two- DVS-retina system, composed of other elements in a chain, which allow us to obtain a distance estimation of the moving objects in a close environment. We will analyze each element of this chain and propose a Multi Hold&Fire algorithm that obtains the differences between both retinas.Ministerio de Ciencia e Innovación TEC2009-10639-C04-0

GPU-based cellular automata simulations of laser dynamics

We present a parallel implementation for Graphics Processing Units (GPUs) of a model based on cellular automata (CA) to simulate laser dynamics. A cellular automaton is an inherent parallel type of algorithm that is very suitable to simulate complex systems formed by many individual components which give rise to emergent behaviours. We exploit the parallel character of this kind of algorithms to develop a fine-grained parallel implementation of the CA laser model on GPUs. A good speedup of up to 14.5 over a sequential implementation running on a single core CPU has been obtained, showing the feasibility of this model to run efficient parallel simulations on GPUs

A Two-Level Dynamic Chrono-Scheduling Algorithm

We propose a dynamic instruction scheduler that does not need any kind of wakeup logic, as all the instructions are “programmed” on issue stage to be executed in pre-calculated cycles. The scheduler is composed of two similar levels, each one composed of simple “stations”, where the timing information is recorded. The first level is aimed to the group of instructions whose timing information cannot be calculated at issue (for example, those instructions whose latency is not predictable). The second level contains simple “stations” for the instructions whose execution and write back cycle have been already calculated. The key idea of this scheduler is to extract and record all possible information about the future execution of an instruction during its issue, so as not to look for this information again and again during wait stages at the reservation stations. Another additional advantage is that time critical parts can be identified as instruction timing information is available, so high speed and frequency logic can be used only in these parts, while the rest of the scheduler can work at lower frequencies, therefore consuming much less power. The lack of wakeup and CAM (Content Addressable Memory) means that power consumption and latencies would be presumably reduced, frequency would probably be made higher, while CPI (clock Cycles Per Instruction) would remain approximately the same.Ministerio de Educación y Ciencia TIN2006-15617- C03-03Junta de Andalucía P06-TIC-0229

Fiabilidad y validez del cuestionario para evaluar la nomofobia (QANP)

Background: The real meaning of the term nomophobia remains somewhat obscure in studies assessing this disorder. There is an increasing interest in further exploring nomophobia: however, currently available measuring tools appear to only address mobile phone abuse and/or addiction. The objective of this study was to create a Spanish-language instrument to measure nomophobia. Methods: We developed an 11-item scale that we administered to 968 participants drawn from the population of Granada (Spain). We first performed an Exploratory Factor Analysis. After assessing the nomological validity of the scale, we conducted a Confirmatory Factor Analysis. Results: The Exploratory Factor Analysis revealed a three-factor structure. Factor 1 (Mobile Phone Abuse) comprised five items that described 19% of the variance; Factor 2 (Loss of Control) comprised three items that explained 12% of the variance; and Factor 3 (Negative Consequences) comprised three items that explained 10% of the variance. Cronbach's Alpha reliability coefficient was 0.80. Limitations: Nomophobia is a modern disorder that has yet to be classified as a disease. Self-report measures are affected by biased replies, and therefore the presence of confounders may be a potential issue. Conclusion: This scale is reliable and valid. It provides future researchers with the means to measure nomophobia in the Spanish population.Antecedentes: El verdadero significado de la nomofobia parece estar oculto en los estudios que evalúan este trastorno. Existe un creciente interés en profundizar en el estudio de la nomofobia, sin embargo, las herramientas de medición disponibles desarrolladas hasta ahora parecen centrarse solo en el abuso y / o adicción a los teléfonos móviles. Por ello, el objetivo de este estudio objetivo proponer y validar un instrumento de medición de la nomofobia para la población española. Método: Desarrollamos una escala con 11 ítems que fue administrada a 968 participantes de la población de Granada (España). En primer lugar se realizó un análisis factorial exploratorio y posteriormente se realizó un análisis factorial confirmatorio. Resultados: El análisis factorial exploratorio reveló una estructura de tres factores. El factor 1 (abuso de teléfonos móviles) está compuesto por cinco ítems y explica un 19% de la varianza; Factor 2 (Pérdida de control) incluye tres ítems y explica el 12% de la varianza y Factor 3 (Consecuencias negativas) contiene tres ítems y explica el 10% de la varianza. El valor del coeficiente de fiabilidad Alpha de Cronbach fue 0.80. Limitaciones: La nomofobia es un trastorno moderno que aún no se ha clasificado como patología, las medidas de autoinforme presentas respuestas sesgadas por lo que podemos encontrar algún error o sesgo. Conclusión: QANP es una escala fiable y válida y proporciona a los investigadores una forma de medir la nomofobia para futuros estudios en la población española

Temperament and characteristics related to nomophobia

Nomophobia is defined as the fear of being out of mobile phone contact and is considered to be a phobia of the modern age. The current study set out to establish the relationship between temperament and personality and the development of nomophobia. The sample was composed of 968 participants selected from the Andalusian population, of which there were 182 males and 785 females aged from 23.19 years. The instruments used were the Questionnaire to Assess Nomophobia (QANIP; Olivencia-Carrión et al., 2018) and the Temperament and Character Inventory Revised (TCI-R; Cloninger et al., 1993). We found that cooperation is a characteristic that significantly reduces nomophobic levels, particularly for the two factors of Mobile Phone Addiction and Negative Consequences. Furthermore, Reward Dependence appears to be positively related to two of the factors involved in nomophobia, namely Mobile Phone Addiction and Loss of Control, suggesting a relationship between Nomophobia and personality. These findings are discussed in terms of their usefulness for identifying the personality predictors of nomophobia in order to develop preventive and intervention strategies

Y cuando todo iba tan bien

Patient with type 2 diabetes mellitus of short evolution and optimal previous metabolic control that presents a subacute (in the last 8 months) severe worsening of glycemic control.Paciente con diabetes mellitus tipo 2 de corta evolución y óptimo control metabólico previo que presenta de forma subaguda (en los últimos 8 meses) franco empeoramiento glucémico

Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming

During the process of reprogramming to induced pluripotent stem (iPS) cells, somatic cells switch from oxidative to glycolytic metabolism, a transition associated with profound mitochondrial reorganization. Neither the importance of mitochondrial remodelling for cell reprogramming, nor the molecular mechanisms controlling this process are well understood. Here, we show that an early wave of mitochondrial fragmentation occurs upon expression of reprogramming factors. Reprogramming-induced mitochondrial fission is associated with a minor decrease in mitochondrial mass but not with mitophagy. The pro-fission factor Drp1 is phosphorylated early in reprogramming, and its knockdown and inhibition impairs both mitochondrial fragmentation and generation of iPS cell colonies. Drp1 phosphorylation depends on Erk activation in early reprogramming, which occurs, at least in part, due to downregulation of the MAP kinase phosphatase Dusp6. Taken together, our data indicate that mitochondrial fission controlled by an Erk-Drp1 axis constitutes an early and necessary step in the reprogramming process to pluripotency

Does Being a Scout Affect Confinement Due to COVID-19? A Comparative Exploratory Descriptive Study with Spanish Adolescents

The pandemic caused by SARS-CoV-2 has caused great social changes, some of them not yet described. This article tries to give an answer to how it has impacted Spanish adolescents in the field of domestic activity and how they use their free time and if there are differences between the normal population and people who have been involved in non-formal education programs, such as Scouts. In addition, young adolescents who actively participate as Scouts have been compared and, if so, belonging to a group has changed their behavior pattern. The sample has been obtained in a probabilistic way representing all the autonomous communities of Spain with a total of 1280 participants. To obtain the data, an online questionnaire was prepared with which qualitative analyzes were subsequently carried out. The results show statistically significant differences in behavior, both in domestic responsibilities and in what they do with their free time. Young Scouts display different behaviors than their non-Scout peers